Folic Acid/Pyridoxine/Cobalamin: Draino for the Carotid Arteries

Folic Acid/Pyridoxine/Cobalamin: Draino for the Carotid Arteries

Reference: Peterson JC, Spence JD. Vitamins and progression of atherosclerosis in hyper-homocysteinaemia. Lancet 1998; 351:263.

Summary: Eighteen male and 20 female patients with ultrasonographically confirmed carotid atherosclerosis agreed to participate in the study. Ultrasound examinations of the carotid arteries were determined twice before and twice after vitamin therapy was instituted. All patients had shown continued, significant plaque growth despite reduction of low-density lipoprotein cholesterol (LDL) levels using cholesterol-lowering drugs before this trial. All subjects began taking 2.5 mg folic acid, 25 mg pyridoxine, and 250 mcg cobalamin daily for a mean of 4.4 years. There was a significant decline in carotid artery plaque after vitamins were begun compared to baseline with no differences for male or female participants. Those over 65 years of age had faster progression of atherosclerosis before the study but, as younger patients did, responded equally to vitamin therapy.

Natural Product Research Consultants, Inc.

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By E. Yarnell

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