Ginkgo, Bilberry and Oxidized LDL

Reference: Francesca Rasetti M, Caruso D, Galli G, Bosisio E. Extracts of Ginkgo biloba L. leaves and Vaccinium myrtillus L. fruits prevent photo induced oxidation of low density lipoprotein cholesterol. Phytomed 1996/7; 3:335-8.

Summary: Low-density lipoprotein cholesterol (LDL) from healthy volunteers without hyperlipidemia was obtained and irradiated with ultraviolet light for eight hours. This normally causes oxidative alterations in the LDL which makes it highly atherogenic. In some samples, varying concentrations of extracts of Ginkgo biloba (standardized to 24% flavone glycosides and 6% terpenes) and Vaccinium myrtillus (bilberry, standardized to 37% anthocyanosides) were added before irradiation. There was a dose- dependent inhibition of oxidation of LDL by both extracts. The concentration of the extracts able to reduce oxidation by 50% was not significantly different for ginkgo or bilberry compared to quercetin. The efficacy of each extract was confirmed by electrophoretic motility studies.

Natural Product Research Consultants, Inc.

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By E. Yarnell

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