Dr. John Beard

Dr John Beard and the The Unitarian Trophoblastic Theory

Here is the truth about cancer and the truth about fact #1. Dr John Beard of Scotland discovered the cause of all cancers and published a paper on The Unitarian Trophoblastic Theory of cancer in 1902. Cancer, while having multifactorial stimuli that will cause the process of the initial replication of the undifferentiated cell, has in fact, one root cause - a deficiency of pancreatic enzymes. Everything else associated, "goes along for the ride" so to speak.

John Beard stated, and later proved clinically, that cancer was the result of failure of the Pancreas to produce proper amounts of pancreatic enzymes. He stated that cells left over from embryonic development of the fetus are scattered throughout our bodies and later in life are occasionally stimulated to begin reproducing. [by some local stimulant such as environmental poison, drug, food, injury etc.] It is the job of pancreatic enzymes to digest these cells the moment they begin to multiply.

In the absence or deficiency of pancreatic enzymes, these primitive cells begin to multiply and the result is cancer, the rapid, uncontrolled growth of undifferentiated cells.

As a result of Beard's announcement, which was promptly rejected by his peers, there soon [by 1911] were forty clinics in London, England curing cancer using crude pancreatic enzymes -however Madam Curie came along and convinced people that Xray was the way to go because it was so "safe" and "effective" and the pancreatic cancer cure was quickly forgotten for several decades.

In the absence or deficiency of Pancreatic enzymes, Sympathetic dominant patients will end up with solid tumors in brain, pancreas, stomach, liver etc., Parasympathetic dominants will end up with the "soft" blood related cancers. The Sympathetic dominants need a more vegetarian based diet, the Parasympathetics need a more meat based/animal protein diet.

The trophoblast cells of pregnancy are typical cancer cells that eat into the uterine lining to prepare the nest. These cells are eventually turned off when the fetal pancreas turns on, otherwise the cancer of pregnancy ensues and kills the mother and baby very quickly. This was the key to Beard's discovery of the link between cancer and pancreatic insufficiency - the fact that in every specie he investigated, it was the turn on of the pancreas that coincided with the end of growth of the trophoblast cells of pregnancy. Trophoblast cells of pregnancy are exactly like cancer cells. Based upon his theory an early cure of a sarcoma was effected by one of his MD friends who injected the pancreatic enzymes - they believed, [incorrectly] that the enzymes needed to be injected because digestion would inactivate them. This is not true, pancreatic enzymes survive digestion and go on to digest cancer cells in the body, [fortunately for us].

Another Beard [Howard] came along and devised the HcG "Anthrone test" to measure female

hormone in the urine. The test is based upon the fact that trophoblast cells of pregnancy, like all cancer cells, excrete HcG. Back in the early seventies these tests were performed on males and females. If you showed the hormone in the urine you were considered to be either a pregnant female or a male or female with cancer.

Howard Beard jokingly stated at the Cancer Control Society seminar back in the seventies that

he had some tumors in his bowel and when they got too big he would stop eating donuts and go back on his pancreatic enzymes to shrink the tumors back down. Back then Laetrile, vitamin B17, was being directly injected into the veins of cancer patients as part of the cure but the nutritional cure rate was only about one third - due to the mistaken idea that everyone needed a vegetarian diet and needed to avoid animal protein.

William Donald Kelley, a dentist from Grapevine, Texas, cured himself of pancreatic cancer in the sixties and went on to develop the present nutritionally based, do-it-yourself home cure for cancer which is probably over ninety per cent effective in patients who have not been overly destroyed by chemotherapy and orthodox treatments.

Noone need die of cancer. However, it is a full time job to cure yourself of cancer. The cause and cure are known and at hand. It has been developed by Kelley over the last thirty years.

While I am at it here this morning let me add one more thing. The literature abounds with nonsense about viruses and how they "cause" all sorts of disease processes and do all sorts of strange and destructive things. Get this point - no virus has life, the minimum requirement of which is metabolism and reproduction which requires a cell wall or at the very least, a membrane. For life to exist there must be the ability to take in energy, metabolize it, and then store the energy in a form of information that will allow reproduction of the thing that is "DOING" the metabolizing and reproducing. Therefore, since no virus has the power of metabolism and reproduction, no virus can "DO" anything. The virus is "DONE TO" by sick cells. A sick cell will produce a "bad" virus. A sick cell might even allow a virus entry into its domain. The cell will then "DO" all the "DOING" that is "DONE" - because the virus - not having any life, cannot "do" anything - a lot of otherwise intelligent men have been led down the path by all this junk science being generated in labs around the country, most of it at taxpayers expense. What we need to do as quickly as possible is, get these people off the dole and get their hands out of the public till. We need to start denying tax money to pursue these stupid projects - and we need to get big government OUT OF THE MEDICAL BUSINESS!!!

Keep in mind that modern medicine has not cured a single degenerative disease. NOT ONE!!! every degenerative disease that has ever been cured has been cured by an essential food factor - not a prescription drug - and every single degenerative disease is caused by either an environmental poison, most of which are introduced into our environment by medical quacks and quack scientists or by malnutrition.

Not one single degenerative disease ever suffered by a human was due to a deficiency in a prescription drug.

William Donald Kelley describes the approach in his momentous book with the extremely humble and deceiving title of "One Answer To Cancer", indeed - it is the ONLY answer to cancer in my studied [over fifty years] opinion.

Dr Daniel H Duffy Sr

Geneva, Ohio


1. Beard, J: "The Action of Trypsin..." Br Med J 4, 140-41, 1906.
2. Beard, J: "The Enzyme Treatment of Cancer" London: Chatto and Windus, 1911.
3. Cutfield, A: "Trypsin Treatment in Malignant Disease" Br Med J 5, 525, 1907.
4. Wiggin, FH: "Case of Multiple Fibrosarcoma Of The Tongue, With Remarks on the Use of Trypsin and Amylopsin in the Treatment of Malignant Disease" JAMA 47, 2003-08. 1906.
5. Gotze, H, Rotham SS: Enterohepatic Circulation of Digestive Enzymes As A Conservative Mechanism" Nature 257 (5527).
6. Shively, FL: "Multiple Proteolytic Enzyme Therapy Of Cancer." Dayton, Johnson-Watson, 1969.
7. Little, WL: "A Case Of Malignant Tumor, WIth Treatment." JAMA 50, 1724, 1908.
8. Kelley, WD: "One Answer To Cancer" latest update - 33,000 cancer cases over three decades. New Century Promotions 3711 Altal Loma Drive Bonita, CA 91902 800-768-8484 or 619-479-3829.
9. Isaacs JP, Lamb J: "Complementarity In Biology, The Quantization Of Molecular Motion" 1969 The John Hopkins Press, Baltimore.

John Beard's Trophoblast Cell Theory

(and a mention of its modern equivalent)

To understand this important group of resources, we need to visit a little bit of scientific history. In 1902 a Scottish doctor, John Beard, published an interesting paper. He drew attention to the fact that when the placenta implants into the uterus, the way it burrows in and invades the mother’s tissue is exactly like a cancer.

Why didn’t the placenta just keep going and take over everything – like a cancer does? Nobody knew at the time but John Beard noticed that the placenta stops invading at exactly the moment when the infants pancreas starts to produce enzymes. If that doesn’t happen, the deadly cancer of pregnancy - chorion-carcinoma - ensues which is capable of killing the mother and baby very quickly (today there is an excellent cure rate for chorion-carcinoma).

The cells of the placenta which invade are called the trophoblasts. Whenever you see the word “tropho” or “trophic” in science, it means feeding. These cells set out to establish the food supply line for the baby fetus.

Beard began to ask himself whether cancer cells, which look exactly like trophoblast cells—young, vigorous, unspecialized—could also be turned off by enzymes from the pancreas. In fact he went even further and speculated that cancer came from hidden trophoblasts cells in the body, left over from days in the womb, which got activated again, by stress and toxins. Perhaps normally these get picked off by enzymes but sometimes they do not and cancer is the result. So Beard called this the trophoblastic theory of cancer.

I think he hit the target right on bullseye and it’s worth making sure you understand the implications of this theory and the treatments which result. Because it does work. Within a few years there were hundreds of clinics which sprang up offering pancreatic enzyme treatments for cancer patients. There were centers 40 in London alone.

Of course it was attacked as nonsense by the medical establishment. They attack everything, from good diet, to surgeons washing their hands and keeping everything clean, to anesthetics. But it wasn’t that which saw Beard’s work disappear. Not long afterwards Madam Curie came along and convinced people that X-ray was the way to go because it was so "safe" and "effective" and the pancreatic cancer cure was quickly abandoned. Marie Curie became famous and John Beard was promptly forgotten (that's called "scientific progress"!).

But the story didn’t die totally. William Donald Kelley, a dentist from Grapevine, Texas, cured himself of pancreatic cancer in the sixties, largely using Beard's theories, and went on to develop a nutritionally-based, do-it-yourself home cure for cancer which is probably over ninety per cent effective in patients who have not been overly destroyed by chemotherapy and orthodox treatments.

Dr. Beard believed the enzymes had to be injected, to prevent destruction by hydrochloric acid in the stomach. However, recent evidence demonstrates that orally ingested pancreatic proteolytic enzymes are acid stable and pass intact into the small intestine, where they are absorbed. Dr Kelley, whose dietary program I referred to in Part 1 of this series, had his own enzymes compounded and they certainly worked.

No-one need die of cancer. However, it is a full time job to cure yourself of cancer. The cause and cure are known and at hand. See the Kelley programme in full.

Dr Nicholas Gonzalez, one of the doctors you should meet if you are interested in this line of treatment, took the time to evaluate Kelley’s work, while still a medical student. Eventually, what began as a student project developed into a two-year formal research effort which he pursued during my formal immunology training. Gonzalez website

Gonzalez reviewed nearly 10,000 of Dr. Kelley's patient records and interviewed over 500 patients with appropriately diagnosed advanced cancer. This included 50 of his patients initially diagnosed with a variety of poor prognosis cancer, all of whom had enjoyed long term survival and/or apparent regression of disease while following their nutritional regimen. Gonzalez also studied 22 patients with near terminal pancreatic cancer. 10 of these patients had visited Kelley only once and had never followed the protocol: these individuals had been discouraged from proceeding largely because of the negative influence of family and physicians who thought Kelley to be an outright fraud. This group of people, sadly, had a survival average of only 60 days, making them a useful control group. Among the remaining 12 patients, Gonzalez found a number who had survived far beyond what would be expected for the disease, including one patient with pancreatic cancer to the liver who had, when last contacted, been alive over ten years from her original diagnosis.

Despite the careful documentation of all these successes, no one in academic medicine could accept that a nutritional therapy might produce positive results with advanced cancer patients.

In 1986, probably as a result of endless pressures, Dr. Kelley gave up research and patient care, and I myself have not spoken to him or any of his associates since 1987. He passed away in January 2005.

But Gonzales pressed on. He carried out a pilot study in 10 patients suffering inoperable adenocarcinoma of the pancreas, with survival as the endpoint. Pancreatic cancer cases were chosen because the prognosis for the disease is so poor, and an effect could be seen in a small number of patients in a short period of time.

Gonzales was told that if three of ten patients lived a year, that would be considered a positive result. What actually happened was that, of 11 patients with only weeks to live, nine (81%) lived one year, 5 lived two years (45%), 4 lived three years (36%) and two have lived longer than four years. You can compare that with a study at about the same time, of the newly approved drug gemcitabine. Of 126 patients with pancreatic cancer not a single patient lived longer than 19 months and yet that was considered a “successful” drug.

I hope you are getting the picture here! Do not listen to the propaganda about conventional treatment. It comes nowhere near the success rate of certain properly run alternative therapies. Yet they call that science. Anyone who tries to help in other ways is attacked bitterly and hounded out of town. One doctor with a cancer cure was shot at repeatedly, until he closed down his clinic.

It’s partly jealous vested interests, guarding its dollars. But pretty plainly it’s also about extravagantly overpaid incompetents and liars not wanting to be shown up for what they are but someone doing a better job for a fraction of the cost.

It should go without saying that you need the proper, the real pancreatic enzymes and not the mediocre substitutes that you buy on the Internet. I’ll tell you a good product shortly. Also it is important to understand you do not simply and only take panreactic enzymes. Kelley had a very strict health regime, covering all aspects of what a patient ate. Gonzales’ therapy itself is quite complex, but basically involves three components: diet, aggressive supplementation with nutrients and enzymes, and detoxification. The protocols are individualized and each patient receives a diet designed for his or her specific needs. The diets are quite variable, ranging from a pure vegetarian program to a diet requiring fatty red meat 2-3 times a day.

The supplement regimens are also individualized, and intense: each cancer patient consumes between 130 and 175 capsules daily. Non-cancer patients will require considerably fewer supplements per day. The supplement regimens include a range of vitamins, minerals, trace elements, anti-oxidants and animal glandular products, prescribed according to the particular patient's needs and cancer type. These nutrients do not, Gonzales believes, have a direct anti-cancer effect, but instead serve to improve overall metabolic function. In addition to these supplements, every cancer patient takes large quantities of freeze dried porcine pancreatic enzymes in capsule form, which Gonzales believe provide the main anti-cancer action.

The animal glandular products and pancreatic enzymes that we use are derived from animals raised in Australia and New Zealand, where there has been no history of BSE (mad cow disease) or other prion diseases such as scrapie. The animal husbandry regulations in Australia and New Zealand are the strictest in the world, and prohibit the feeding practices that have caused problems in other countries.

The third component of the protocol involves what we call "detoxification" routines. On this therapy, we find that as patients repair and rebuild, large amounts of metabolic wastes and stored toxins are released. As a result, patients routinely develop a variety of symptoms, most commonly described as "flu-like," such as low grade fevers, muscle aches and pains, even rashes which may be from destruction of the tumor or just from removing the chemical pollutants I referred to in part 1.

Part of "Detoxification" refers to procedures such as the coffee enema, which are believed by alternative practitioners to stimulate liver function and in turn, the processing and excretion of metabolic wastes. The coffee enemas are done twice daily, and patients most commonly report symptomatic relief.

Coffee enemas have been discussed in the orthodox medical literature for the better part of this century. Many nursing texts routinely recommended coffee enemas, and the Merck Manual advocated coffee enemas as a stimulant in all editions from the first in 1898 through 1977.

So there is a lot to the pancreas enzyme approach. Let me now give you some understanding from modern science, which makes it almost imperative that you take at least SOME quality enzymes.

There are many enzymes in biology, indeed a dazzling array for every function of the cell. Enzymes make important chemical reactions occur at body temperature, which otherwise might need heat. But here we mean digestive enzymes or their equivalent, usually from animal pancreas sources. Bromelain (from pineapple) and papain (from papaya) are also able to digest proteins and other complex biological molecules, safely and effectively. Why is this important?

Most tumours and cancer cells are covered by a sticky resistant mucous/protein coating, which makes them safe from immune cells and even protects them to a degree, from chemotherapy. We can use a mixture of enzymes to dissolve away this protective coat, leaving the cancer cell naked and vulnerable. It can then be poisoned and quickly gobbled up by the body’s defences. It will also help chemo because the deadly chemical will be more likely to reach the core of the cancer cells and choke it to death.

There are many enzymes replacement products on the market. Look for preoteolytic enzyme (trypsin) or pancreas-type names (Pancreatin, or such), or even pancreas extract. Enzyme mixtures of this sort cool inflammation and so they also have a use against heart disease and blood clotting disorders, arthritis, asthma, and inflammatory bowel disorders. Alternative doctors will take an enzyme formula after sports exertion, to curb the aches and pains (which are also largely inflammatory in nature).

But the important role here is that of stripping off the protective coating from cancer cells.

A number of proprietary brands exist, of which I can recommend German brand Wobenzyme, available widely. A typical dose regime would be 12- 20 capsules a day. As a proprietary product, it tends to be expensive. Wobenzyme contains bromelain, papain, as well as trypsin, chymotrypsin and pancreas extract.


Beard, J: "The Action of Trypsin..." Br Med J 4, 140-41, 1906.
Beard, J: "The Enzyme Treatment of Cancer" London: Chatto and Windus, 1911.
Cutfield, A: "Trypsin Treatment in Malignant Disease" Br Med J 5, 525, 1907.
Wiggin, FH: "Case of Multiple Fibrosarcoma Of The Tongue, With Remarks on the Use of Trypsin and Amylopsin in the Treatment of Malignant Disease" JAMA 47, 2003-08. 1906.
Gotze, H, Rotham SS: Enterohepatic Circulation of Digestive Enzymes As A Conservative Mechanism" Nature 257 (5527).
Shively, FL: "Multiple Proteolytic Enzyme Therapy Of Cancer." Dayton, Johnson-Watson, 1969.
Little, WL: "A Case Of Malignant Tumor, WIth Treatment." JAMA 50, 1724, 1908.
Kelley, WD: "One Answer To Cancer" latest update - 33,000 cancer cases over three decades. New Century Promotions 3711 Alta Loma Drive Bonita, CA 91902 800-768-8484 or 619-479-3829.

Pancreatic Cancer, Proteolytic Enzyme Therapy and Detoxification

Excerpted with permission from the November 1999 Clinical Pearls News
Kirk Hamilton: What is your educational background and current position?

Nicholas J. Gonzalez: I graduated from Brown University, Phi Beta Kappa, Magna Cum Laude with a degree in English literature. I did my premedical work as a postgraduate student at Columbia University, and received my medical degree from Cornell University Medical College in New York. I subsequently completed a year of internship in internal medicine, and a fellowship in immunology.

KH: Where did you come up with the idea at all to use pancreatic enzymes in cancer and what is the theoretic mechanism?

NJG: I didn’t come up with the idea to use pancreatic enzymes to treat cancer. The Scottish embryologist, John Beard, who worked at the University of Edinburgh at the turn of the century, first proposed in 1906 that pancreatic proteolytic enzymes, in addition to their well-known digestive function, represent the body’s main defense against cancer. He further proposed that pancreatic enzymes would most likely be useful as a cancer treatment. During the first two decades of this century, a number of physicians, both in Europe and in the United States, used injectable pancreatic enzymes to treat advanced human cancer, often times (depending on the quality of the product) with great success. I have collected a number of reports from that time in the major medical journals documenting tumor regression and long-term survival in patients treated with enzyme therapy. In my first article, I mentioned that in 1911, Dr. Beard published a monograph entitled The Enzyme Therapy of Cancer, which summarized his therapy and the supporting evidence. [Available through New Spring Press]

After Dr. Beard's death in 1923, the enzyme therapy was largely forgotten. Periodically, alternative therapists have rediscovered Dr. Beard's work, and used pancreatic proteolytic enzymes as a treatment for cancer.
I began researching the use of oral pancreatic proteolytic enzyme therapy as a treatment for cancer after completion of my second year at Cornell University Medical College in 1981. My research advisor at the time supported and directed my early work, and later supported me during my formal immunology fellowship. In terms of the theoretical foundation, the exact mechanism of action has never been demonstrated. After Beard’s death, the enzyme therapy was largely forgotten and certainly never generated any significant research effort until recently with the funding of my work. There are several studies from the 1960s showing, in an animal model, that orally ingested pancreatic enzymes have an anti-cancer effect, and might work through immune modulation, but these studies were preliminary and were never followed-up. Dr. Beard believed enzymes had to be injected to prevent destruction by hydrochloric acid in the stomach. However, recent evidence demonstrates that orally ingested pancreatic proteolytic enzymes are acid stable, pass intact into the small intestine and are absorbed through the intestinal mucosa into the blood stream as part of an enteropancreatic recycling process.

It is clear from our extensive clinical experience that pancreatic proteolytic enzymes have a profound anti-neoplastic effect, but we do not know how they work. We have not had the resources to support basic science research, but with appropriate funding we do not believe it would difficult to set up animal models to explore the molecular action of the enzymes against cancer cells.

KH: Why did you choose a vegetable-based diet, low in red meat and poultry, with a little fish and occasional dairy products?

NJG: We divide patients into different metabolic categories, depending on each patient’s particular genetic, biochemical and physiological make-up. In this model, patients with solid epithelial tumors, such as tumors of the lung, pancreas, colon, prostate, uterus, etc. do best on a largely plant-based diet. Such patients have a metabolism that functions most efficiently with a specific combination of nutrients that are found in fruits, vegetables, nuts, whole grains and seeds, and with minimal to no animal protein.

On the other hand, patients with the blood or immune based malignancies such as leukemia, myeloma and lymphoma do best on a high-animal protein, high-fat diet. Such patients do extremely well with a diet based on animal products with minimal to moderate amounts of plant based foods, the particular design of the diet again depending on the individual patient’s metabolic make-up. We find patients with pancreatic cancer always do best with a largely plant-based diet that emphasizes fruits, vegetables and vegetable juice, nuts, seeds and whole grains. Allowed protein includes fish one to two times a week, one to two eggs daily and yogurt daily, but no other animal protein. In our therapy, we use diets specifically because of the effect of food on the autonomic nervous system. This system consists of the sympathetic and parasympathetic branches and ultimately controls all aspects of our physiology, including immune function, cardiovascular activity, endocrine function and the entire action of our digestive system. The sympathetic and parasympathetic systems have opposing actions on the target organs and so can adjust our physiology depending on needs and demands, enabling our bodies to react to any situation, condition or stress. We believe disease, whatever the form, occurs because there is an imbalance in autonomic function. For example, we find solid tumors, such as tumors of the breast, lung, pancreas, colon, uterus, ovaries, liver, etc occur only in patients who have an overly strong sympathetic nervous system and a correspondingly weak, ineffective parasympathetic nervous system. We believe that blood-based cancers, such as leukemia, lymphoma and multiple myeloma, only occur in patients that have an overly developed parasympathetic nervous system, and a correspondingly weak sympathetic nervous system. Previous research, such as Dr. Francis Pottenger’s research during the 1920s and 1930s proposed that much if not all disease has autonomic imbalance as at least one of the major causes.

We have found that specific nutrients and foods have specific, precise and predictable effects on the autonomic nervous system. For example, a vegetarian diet emphasizes fresh fruits and vegetables, particularly leafy greens, and contains large doses of minerals such as magnesium and potassium. It has been shown in many studies that magnesium suppresses sympathetic function, while potassium stimulates parasympathetic activity. Furthermore, a largely vegetarian diet tends to be very alkalinizing, and the neurophysiologic research documents that in an alkalinizing environment, sympathetic activity is reduced and parasympathetic activity increased. So, whatever other effect a vegetarian diet has, in terms of autonomic nervous system function, such a diet will reduce sympathetic activity and stimulate the parasympathetic system.

A meat diet is loaded with minerals such as phosphorous and zinc, which tend to have the opposite effect. A high-meat diet stimulates the sympathetic system and tones down parasympathetic activity. Furthermore, such a diet is loaded with sulfates and phosphates that in the body are quickly converted into free acid, that in turn stimulates the sympathetic nervous system while suppressing parasympathetic activity.

So, by the careful use of diet, we are able to effect major changes in autonomic function, and bring about balance in a dysfunctional nervous system. We find, further, as the autonomic system comes into greater harmony and balance, when the autonomic branches are equally strong, all systems – from the immune system to the cardiovascular system – work better regardless of the underlying problem. In essence, we are using diet to bring about greater physiological efficiency. For cancer patients, long experience has taught us that it is not enough to load patients with enzymes; the question of autonomic imbalance must also be addressed. In terms of pancreatic patients specifically, a plant-based diet provides all the nutrients to correct autonomic dysfunction.

KH: Can you describe the vitamin and mineral supplement regimen you used? Was it megadoses or a basic nutritional support?

NJG: All of our patients, whether they have cancer or some other problem, consume specific combinations of vitamins, minerals, trace elements, amino and fatty acids, and animal-derived glandular and organ concentrates. We use such supplements very specifically, in very precise doses and combinations as we use diet, to manipulate autonomic function and to bring about balance to an imbalanced system. Certain vitamins, minerals and trace elements, such as many of the B vitamins and, as mentioned above, magnesium and potassium, tone down the sympathetic nervous system and stimulate the parasympathetic nerves. Other nutrients, particularly calcium, phosphorous and zinc, stimulate the sympathetic system but weaken the parasympathetic system. By the use of precise combinations of vitamins, minerals and trace elements, along with diet, we are able to bring about balance to the autonomic system. And, again, when the autonomic branches come into balance, the patients, whatever the underlying disease, do better.

KH: What is the role of coffee enemas in this particular treatment and what is the history of coffee enemas in traditional medicine?

NJG: When I first began my research efforts, I was very surprised to find that the coffee enemas, often portrayed as one of the most bizarre aspects of alternative medicine, came right out of the Merck Manual, a revered compendium of orthodox treatments. When I was completing my immunology fellowship, I had an interesting correspondence with the then editor of the Merck Manual, who confirmed that the coffee enemas had been advocated in the Merck Manual from about 1890 right up until 1977, when they were removed more for space considerations than anything else. Most nursing texts for the better part of the century recommend coffee enemas. Particularly during the 1920s and 1930s coffee enemas were used in the US and abroad to treat a variety of conditions, and I have put together a library of articles from that time discussing the wide ranging effects on patients. Coffee enemas were frequently recommended because patients, whatever their underlying problem, tended to feel better after a coffee enema. I have followed thousands of patients over the years who have done coffee enemas in some cases for decades: virtually all patients report an increase sense of well being. I have done them myself daily since first learning about them in 1981.

There is research going back to the earlier part of the century that indicated that coffee enemas stimulate more efficient liver function and gallbladder emptying, and we believe that is the primary therapeutic benefit. Particularly with cancer patients, who often have a very large tumor burden, as the body repairs and rebuilds and as tumors break down, enormous amounts of toxic debris can be produced, much of which must be processed in the liver. The coffee enemas seem to enhance this processing of toxic metabolic waste. Interestingly enough, in Hospital Practice (August 15, 1999 page 128), a very orthodox journal of internal medicine, I read a summary of an article showing coffee seems to enhance gallbladder and liver function.

KH: Is it possible that the positive effects from the coffee enemas are a result of a "caffeine high" versus a metabolic benefit?

NJG: The issue of a caffeine high is often raised. I don’t believe this is the case at all. First, patients almost universally report a relaxing effect, not the stimulation you find with coffee taken orally. Many patients, in fact, fall asleep while doing the enemas. I, myself, have never been able to tolerate drinking coffee because coffee, when drunk, causes in me an amphetamine like response. However, I always feel relaxed when I do a coffee enema and often fall asleep. Something completely different is going on with the enemas.

KH: Can you describe your study and the basic results?

NJG: In July 1993, the then Associate Director for the Cancer Therapy Evaluation Program at the National Cancer Institute, Dr. Michael Friedman, invited me to present selected cases from my own practice as part of an NCI effort to evaluate non-traditional cancer therapies. I prepared for presentation 25 cases with poor prognosis or terminal illness who had either enjoyed long-term survival or tumor regression while following my program. After the session, Dr. Friedman suggested we pursue a pilot study of our methods in 10 patients suffering inoperable adenocarcinoma of the pancreas, with survival as the endpoint. Because the standard survival for the disease is so poor, an effect could be seen in a small number of patients in a short period of time.

Nestec (the Nestle Corporation) agreed to fund the trial, which began in January 1994. The study has been completed and was published in Nutrition and Cancer, June, 1999;33(2). Of 11 patients followed in the trial, eight of 11 suffered stage four disease. Nine of 11 (81%) lived one year, five of 11 lived two years (45%), and four of 11 lived three years (36%). Two are alive and well with no signs of disease, one at 3.5 years and one at 4.5 years. In comparison, in a recent trial of the newly-approved drug gemcitabine, of 126 patients with pancreatic cancer not a single patient lived longer than 19 months. [Abstract]

As a result of the pilot study, the National Cancer Institute approved $1.4 million over five years for a large scale, randomized clinical trial comparing my nutritional therapy against gemcitabine in the treatment of inoperable pancreatic cancer. This study has full FDA approval and is being conducted under the Department of Oncology and the Department of Surgical Oncology at Columbia Presbyterian Medical Center in New York. The trial is the outgrowth of a Congressional hearing last summer encouraging intensive government evaluation of promising alternative cancer treatments, and is currently up and running.

KH: Were there any side effects to this high dose (130 and 160 capsules per day) of pancreatic enzymes? It seems like that would cause some significant gastrointestinal irritation.

NJG: The only side effects I have noticed in 12 years of treating cancer patients with high dose porcine-based pancreatic enzyme therapy are intestinal gas, occasional bloating, and occasional indigestion. Frankly, the side effects tend to be very minimal. The enzymes we use are made specially for my patients in New Zealand. I believe most pancreatic enzymes available either as a prescription or over the counter in health food stores are not effective against cancer. We actually had to develop a manufacturing process to produce what I think are the appropriate enzymes, and they are not available except to my patients. Until we prove the benefit of my work, I don’t think it is appropriate to mass market the enzymes. I also don’t think it appropriate for cancer patients to try and treat themselves.
KH: How compliant were your patients to this regimen?

NJG: Pancreatic cancer patients are notoriously medically unstable, and some patients in the study were so weak they had difficulty complying fully at times, although many of the patients did comply well. Generally, we find that the better the compliance, the better the effect of the treatment. Patients in the trial came from all over the country, and because our approach is still alternative, patients were not allowed to continue the treatment when hospitalized. In the Columbia study, all patients are going to be treated aggressively for underlying medical problems and will be encouraged to continue their therapy at all times.

KH: What would you like to see in the future with regard to evaluating this protocol as far as studies go?
NJG: As above, we are involved in a large scale, NCI-funded, FDA-approved randomized clinical trial at Columbia University.

KH: What feedback have you gotten from the traditional oncology community with regard to your work?
NJG: The attitude is changing; for example, I have sent you a very supportive article about my work that appeared in the magazine InTouch, a news style magazine that is sent to more than 90,000 orthodox physicians, including all oncologists in this country. The oncology newspaper Oncology News International had a very nice piece about my research efforts, and I have sent you a copy of that story. I have also sent a copy of a press release in support of our work sent out from Congressman Dan Burton, Chairman of the Committee on Government Reform.

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