Vitamin E and Prostate Cancer: Is Vitamin E Succinate a Superior Chemopreventive Agent?

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VITAMIN E
VITAMINS, Fat-soluble
PROSTATE -- Cancer
CANCER
CHEMOPREVENTION
MEDICINE, Preventive
PHARMACOLOGY

Abstract:There is convincing evidence that vitamin E succinate significantly reduces human prostate cancer growth in experimental models compared with ?-tocopherol or tocopheryl acetate. Its intact delivery to cancer cells is questionable when administered orally; however, a study in transgenic mice showed a synergistic inhibitory effect of dietary vitamin E succinate, selenium, and lycopene on prostate cancer incidence. Clinical trials have yet to confirm this effect.

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