A Homeopathic Proving of Candida Parapsilosis

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A Homeopathic Proving of Candida Parapsilosis

Candida parapsilosis is a common yeastlike organism that has been implicated in human infection. It has been recovered from respiratory secretions, urine, gastric washings, blood, vagina, oropharynx, skin, trans tracheal aspiration, stool, pleural fluid, ear, and nails( 1). It is implicated in the following human infections: endopthalmitis, endocarditis, vaginitis, mycotic keratitis, external otomycosis, paronychia, and fungemia. In the vagina, it is found less frequently than Candida albicans and Torulopsis glabrata and is only rarely associated with vulvovaginal candidiasis as it is a less adherent organism( 2, 3).

Between September 10, 1989 and October 2, 1989, we performed a homeopathic proving of C. parapsilosis.

METHODS

Prover selection and population size. Twenty participants, ages 25-65 years old were recruited to participate in the proving. Prior to entrance to the study each participant was interviewed for any concurrent illness and had a baseline CBC and urine analysis performed. Exclusion criteria also included concurrent use of a homeopathic remedy, any prescription medications, and history of a Candida species infection within the last year. Following the above screening procedures and subsequent dropout of four participants, the final population size was 16 (nine females and seven males).

MEDICATION

A mother tincture of Candida parapsilosis was prepared by Sanum-Kehlbeck GmbH & Co KG in Hoya, West Germany. A 12x dilution of the mother tincture was prepared by Chiron Consultants, Inc. in Calgery, Alberta (Canada). The 12x dilution Was later increased to a 30x dilution by Life-Force Homeopathics in Brea, Cy. The Pharmacy of the Natural Health Clinic of Bastyr College prepared two 2-dram vials, containing #20 lactose pellets, for each participant labelled "tube A" and "tube B" with the participant's code number on each vial. The test medication was randomly placed in either "tube A" or "tube B" for each participant with the other tube containing placebo. The code was retained by the pharmacy until the end of the proving and the participants and the principal investigators were blind to the content of each tube.

PROCEDURE

The proving received the approval of the Institutional Review Board of Bastyr College. Participants meeting entry criteria were asked to sign an informed consent form. They then were instructed in the recording of symptoms and were asked to discontinue the use of any stimulants including caffeine and tobacco.

Participants were then dispensed their "tube A" by the pharmacy of the Natural Health Clinic of Bastyr College and were instructed to take one dose four times daily between meals for seven days. At the end of the first seven day period, participants were instructed to stop their "tube A" and were asked to continue recording their daily symptoms for another five days. At the end of this period, they were asked to report to the principal investigators with their first twelve-day symptom reporting log. Following a brief interview, participants were dispensed their "tube B" with the instructed to take the test medication four times daily for seven days. Another five day, medicine-free recording period followed.

At the conclusion of the second twelve day cycle, participants were asked to return their "tube B" symptom log. Each participant was compensated for their participation in the proving. Participants were also asked to report the unfolding of any other symptoms and were informed that there would be follow-up. Following retrieval of all of the participants logs, the code was broken and given to the participating investigators.

RESULTS/SYMPTOMOLOGY

MIND

Very tired and scatter-brained.

Total "loss of mind": seeing red lights and thinking they were green.

Mind races and words come out in wrong order or mispronounced.

Spacey and poor concentration. Concentration difficult (several provers).

Extremely anxious.

More easily aggravated and frustrated.

Explosive anger at minor incidents - as though their rights were being infringed upon.

Forgetful

Unusually irritable.

VERTIGO

Dizziness and hot flushes - better in open air.

HEAD

Pain - Frontal constriction: worse in direct sunlight.

Wakes with a headache - `banging' sensation.

Outer edges of scalp itch.

Eczema-like patches on hairline - red, scaly and itching.

Itching of scalp: Dry, flaking, reddened spot along hairline.

`Sick' headache with frontal aching and mild throbbing.

EYES

Itching ( 2)

Burning pain - wakes at 1 a.m. with burning eyes.

Eyes bloodshot - worse medial to iris.

NOSE

Sneezing

Left nostril bleeding - bright red block

Stuffiness (3 provers).

FACE

Tiny, white pimples with dry skin.

Lower lip burning and tingling.

Lower lip: Small dry patch- flaking skin (1 x 1/2 cm)

Swollen feeling around face - sensation of fine vibration.

MOUTH

Burning and tingling of mouth and lower lip with a hot feeling down the esophagus into the stomach.

Boil on buccal mucosa of left cheek.

Woke with hive-like swelling of lower lip.

Tingling of lips immediately after taking medication.

Sensitive nodules on posterior tongue bilaterally - like an aptheous ulcer.

THROAT

Itching throat.

Woke at one a.m. with burning throat and thirst.

STOMACH

Decreased appetite ( 1)

Very thirsty

Increased appetite ( 3)

Craves salt ( 2)

Craves pickles and garlic

ABDOMEN

Abdominal cramping four hours after eating lunch - better with flatulence.

Abdominal cramping five hours after lunch.

Gas and bloating after eating with heartburn.

Fullness in stomach two hours after eating - duration of seven days.

Flatulence - odorous and frequent with lower abdominal cramps.

Lower left quadral abdominal pain - cramps.

RECTUM

Constipation ( 2)

STOOL

Well-formed and hard.

Loose stools.

Green, acidic stools.

BLADDER

Increased urge to urinate.

URINE

Intense smelling urine. Strong-smelling urine with very dark, yellow color.

GENITALIA MALE

Decreased sexual desire.

GENITALIA FEMALE

Itching in pubic hair - red and sore - better with bathing.

Vaginal itching.

Clear vaginal discharge.

Fertile mucous for the entire active proving (7 days) when 1-2 days is normal.

Menses eight days late.

Egg-white leucorrhea - dripping discharge.

LARYNX AND TRACHEA

Heartburn

Esophageal reflux

Burning and tingling with hot sensation down esophagus.

CHEST

Sensation of arrhythmias with light-headed feeling.

Prominent, quick heartbeat which reverberates through the chest.

Violent heat flutter for five seconds which caused immobilizing fear - occurred while lying on left side.

Worst premenstrual breast-tenderness ever.

EXTREMITIES

Woke with hive-like swelling on the right hip.

Forearms very itchy and slightly red on volar surface - worse with a wool shirt on.

Itchy heel - pruritus.

Two, small vesicles on right arm under watch - very red and itchy.

BACK

Recurring, burning spot on medial border of left scapula - feels as if stung by a scorpion. Upper, lateral aspect of right scapula - point feels as if bitten but no lesion present.

SKIN

Pimple-like sore on buttocks - pink and raised and sore to touch.

Itching all over as if a bug or other irritant were on skin scratching skin relieves temporarily.

REFERENCES
(1.) E.W. Koneman and G.D. Roberts, "Clinical and Laboratory Diagnosis of Mycotic Disease," Clinical diagnosis and Management by Laboratory Methods (ed. Henry JB), W.B. Saunders Company, Philadelphia, 1979.

(2.) K.K. Holmes, "Lower genital tract infections in women: Cystitis/urethritis, vulvovaginitis, and cervicitis," Sexually Transmitted Diseases (eds. Holmes KK & Mardh PA).

(3.) J.D. Oriel et al., "Genital yeast infections," Br. Med. J. 4:761,1972.

Chiropractic Academy of Homeopathy.

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By Donald Brown and Andrew Lange