OXIDATIVE STRESS IN AUTISM

Tagged:  

AUTISM
OXIDATIVE stress
DEVELOPMENTAL disabilities
OXIDATION-reduction reaction
TRACE element deficiency diseases
BIOMOLECULES

Abstract:This article outlines data and concepts which suggest that greater oxidative stress in autism may be important in the expression of autistic symptoms and the pathogenesis of autism, a behavioral disorder with hallmark communication and social deficits. Oxidative stress, impaired energy production and excitotoxicity are dynamically related. Lower zinc status in autism is clearly established. Red-cell zinc, a sensitive indicator of zinc sufficiency is significantly lower in the autistic group. Optimistically, it is noted that oxidative damage to biomolecules is often at least partially reversible.

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