Sytrinol Natural Cholesterol Lowering Breakthrough


Cardiovascular disease (CVD) is the number one cause of death in America. Accounting for more than 1.4 million deaths each year, it claims as many lives as the next 14 leading causes of death combined. Elevated cholesterol levels, particularly LDL cholesterol, which can be determined by a simple blood test, are considered to be one of the primary precursors of CVD.

The pharmaceutical approach for hypercholesterolemic people is to use cholesterol-lowering medications called statins. Commonly used drugs in this category include atorvastatin (Lipitor), cerivastatin (Baycol), lovastatin (Mevacor), pravastatin (Pravachol) and simvastatin (Zocor). Statins are the top-selling drugs in America with projected sales in 2004 to reach $19 billion; however, statins are associated with many negative side effects including liver problems, cancer, nerve damage and depletion of CoQ10. High cholesterol is being diagnosed in younger individuals more than ever before, raising the specter that people could be taking statin drugs for their entire adult lives. The consequences of taking a statin drug for 50 or more years are not known, however their side effects are. The cumulative effect of these side effects for such an extended period cannot be beneficial. Another consideration is that statins should be reserved for individuals with chronically high cholesterol levels who are at serious risk, whereas a more benign solution should be adopted for individuals who just have elevated cholesterol and simply want to get their levels back into a normal healthy range.

As CVD (cardiovascular disease) holds steady as the top disease, it is certain that a large percentage of health conscious consumers are seeking a natural solution to the cholesterol problem without the side effects of pharmaceutical drugs.

Most of us are aware there are lifestyle modifications which can help to reduce cholesterol levels. However, estimates show that 75 percent of people suffering from high cholesterol levels are not able to use diet to control their cholesterol because their liver produces high amounts of cholesterol regardless of dietary cholesterol intake.

Contrary to popular belief, cholesterol consumed in food is minor compared to the amount of cholesterol produced in the body. Only 20 percent of cholesterol comes from the foods we eat and 80 percent is produced by the liver.

Sytrinol™--Patented Synergistic Formula
The need in the market is clear and Sytrinol represents an exceptional solution. Sytrinol is a patented proprietary formula which is proven to inhibit the synthesis of cholesterol produced by the liver it is derived from natural citrus and palm fruit extracts. Sytrinol combines citrus polymethoxylated flavones (PMFs), palm tocotrienols and other proprietary constituents. This combination results in a synergistic effect for significantly lowering total cholesterol, LDL cholesterol and triglyceride levels. Sytrinol has also been shown to increase HDL levels. Additionally, Sytrinol is a powerful antioxidant with numerous heart health benefits and plays a significant role as an anti-inflammatory.

The benefits of Sytrinol have been shown in vitro, in vivo, and in multiple clinical studies. In these studies, hypercholesterolemic subjects consumed 150 mg of Sytrinol twice per day (300 mg/day) and were instructed to keep the same dietary habits and maintain their caloric intake during the study. Fasting blood samples were drawn at the onset of the study and at the end of four weeks for analysis of total cholesterol, LDL cholesterol and total triglycerides. The results of the clinical studies were all similar in their effect, with an average reduction of total cholesterol by 25 percent, LDL cholesterol by 23 percent and total triglycerides by 28 percent. Additionally, the LDL/HDL ratio was significantly reduced in all clinical studies by an average of 24 percent.

SourceOne Global Partners, the international distributors of Sytrinol, is committed to continued research regarding the heart health benefits of this cutting-edge formula. They have just completed phase I (12 weeks) of a three phase, double-blind, randomized 24-week study on 120 hypercholesterolemic subjects. The results are even more compelling than the previous clinical studies on Sytrinol's heart health benefits.

An additional and very important benefit of Sytrinol that cannot be claimed by other cholesterol lowering supplements is the anti-inflammatory component. Inflammation is indicated as one of the main culprits in cardiovascular disease. Epidemiological studies show that cardiovascular disease is affecting younger individuals; one third of those were in good health and their cholesterol was within normal range. Both men and women in this group can suffer from sudden heart attacks with no warning signs or risk factors known to cause heart disease. Recent research is establishing that inflammation may cause c reactive protein (CRP) to be produced in the body, a known marker for sudden heart attack. Specific PMFs have a wealth of science indicating their anti-inflammatory properties dating back to the 1960s. It is theorized that the citrus flavonoids found in Sytrinol, particularly the PMFs, would likely have an effect on CRP. Researchers have shown that the presence of CRP in the body is a more reliable predictor of a pending heart attack than any other traditionally known risk factor for heart disease.

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By Richard F. Staack, Ph.D.

Richard Staack, Ph.D. is the vice president of Business Development, Technology and Science at SourceOne Global Partners. Dr. Staack has 15 years of experience in the dietary supplement and functional food area. He was the assistant director of Human Nutrition Research Program for NCBA responsible for developing and managing clinical trials. He was a senior scientist for Henkel Nutrition & Health, responsible for scientific information on pycnogenol, isoflavones, vitamin E and other product lines.

Dr. Staack received his Master of Science and Doctorate in Nutritional and Biochemical Toxicology from the University of Illinois, Urbana-Champaign. He is associated with numerous professional affiliations and has published several articles on nutrition and toxicology in peer reviewed journals.

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