Water is an essential nutrient (macro-nutrient). Water is essential for all energy production in the body. Water is also used for temperature regulation and waste elimination and is essential to cell processes. An inadequate supply of water can result in up to a 30% reduction of energy. Between 50% and 70% of the body weight is water. Insufficient water in the body results in a decrease of blood volume thereby reducing the overall oxygen transport ability of the blood to properly supply the muscles during exercise.

Vitamins are organic components in food that are needed in very small amounts for growth and for maintaining good health. The vitamins include vitamin D, vitamin E, vitamin A, and vitamin K, or the fat-soluble vitamins, and folate (folic acid), vitamin B12, biotin, vitamin B6, niacin, thiamin, riboflavin, pantothenic acid, and vitamin C (ascorbic acid), or the water-soluble vitamins. Vitamins are required in the diet in only tiny amounts, in contrast to the energy components of the diet.

Enzymes are biological catalysts, or chemicals that speed up the rate of reaction between substances without themselves being consumed in the reaction. As such, they are vital to such bodily functions as digestion, and they make possible processes that normally could not occur except at temperatures so high they would threaten the well-being of the body. A type of protein, enzymes sometimes work in tandem with non-proteins called coenzymes.

Amino acids are the building blocks of protein. Twenty amino acids are needed to build the various proteins used in the growth, repair, and maintenance of body tissues. Eleven of these amino acids can be made by the body itself, while the other nine (called essential amino acids) must come from the diet. The essential amino acids are isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. Another amino acid, histidine, is considered semi-essential because the body does not always require dietary sources of it.

Proteins are nutrients. Along with carbohydrates and fat, your body needs protein, a nutrient made up of essential and nonessential amino acids, for good health. Your body manufactures 13 nonessential amino acids, which aren't available from food. For the body to process protein properly, the foods that you eat must contain the nine essential amino acids that are available only from dietary sources.